Selected Publications:
Kenanova, V. Olafsen, T. Crow, D. M. Sundaresan, G. Subbarayan, M. Carter, N. H. Ikle, D. N. Yazaki, P. J. Chatziioannou, A. F. Gambhir, S. S. Williams, L. E. Shively, J. E. Colcher, D. Raubitschek, A. A. Wu, A. M. Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments.
Cancer Research.
2005;
65(2):
622-631.
Jan, S. Santin, G. Strul, D. Staelens, S. Assie, K. Autret, D. Avner, S. Barbier, R. Bardies, M. Bloomfield, P. M. Brasse, D. Breton, V. Bruyndonckx, P. Buvat, I. Chatziioannou, A. F. Choi, Y. Chung, Y. H. Comtat, C. Donnarieix, D. Ferrer, L. Glick, S. J. Groiselle, C. J. Guez, D. Honore, P. F. Kerhoas-Cavata, S. Kirov, A. S. Kohli, V. Koole, M. Krieguer, M. van der Laan, D. J. Lamare, F. Largeron, G. Lartizien, C. Lazaro, D. Maas, M. C. Maigne, L. Mayet, F. Melot, F. Merheb, C. Pennacchio, E. Perez, J. Pietrzyk, U. Rannou, F. R. Rey, M. Schaart, D. R. Schmidtlein, C. R. Simon, L. Song, T. Y. Vieira, J. M. Visvikis, D. de Walle, R. V. Wieers, E. Morel, C. GATE: a simulation toolkit for PET and SPECT.
Physics in Medicine and Biology.
2004;
49(19):
4543-4561.
Rannou, F. R. Kohli, V. Prout, D. L. Chatziioannou, A. F. Investigation of OPET performance using GATE, a Geant4-based simulation software.
Ieee Transactions on Nuclear Science.
2004;
51(5):
2713-2717.
Huang, S. C. Wu, H. M. Shoghi-Jadid, K. Stout, D. B. Chatziioannou, A. Schelbert, H. R. Barrio, J. R. Investigation of a new input function validation approach for dynamic mouse microPET studies.
Molecular Imaging and Biology.
2004;
6(1):
34-46.
Inubushi, M. Jordan, M. C. Roos, K. P. Ross, R. S. Chatziioannou, A. F. Stout, D. B. Dahlbom, M. Schelbert, H. R. Nitrogen-13 ammonia cardiac positron emission tomography in mice: effects of clonidine-induced changes in cardiac work on myocardial perfusion.
European Journal of Nuclear Medicine and Molecular Imaging.
2004;
31(1):
110-116.
Sundaresan, G. Yazaki, P. J. Shively, J. E. Finn, R. D. Larson, S. M. Raubitschek, A. A. Williams, L. E. Chatziioannou, A. F. Gambhir, S. S. Wu, A. M. I-124-labeled engineered Anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice.
Journal of Nuclear Medicine.
2003;
44(12):
1962-1969.
Tai, Y. C. Chatziioannou, A. F. Yang, Y. F. Silverman, R. W. Meadors, K. Siegel, S. Newport, D. F. Stickel, J. R. Cherry, S. R. MicroPET II: design, development and initial performance of an improved microPET scanner for small-animal imaging.
Physics in Medicine and Biology.
2003;
48(11):
1519-1537.
Inubushi, M. Wu, J. C. Gambhir, S. S. Sundaresan, G. Satyamurthy, N. Namavari, M. Yee, S. Barrio, J. R. Stout, D. Chatziioannou, A. F. Wu, L. L. Schelbert, H. R. Positron-emission tomography reporter gene expression imaging in rat myocardium.
Circulation.
2003;
107(2):
326-332.
Chatziioannou, A. F. Small animal Imaging using positron emission tomography.
Neurotoxicology.
2003;
24(2):
287-288.
Bai, B. Li, Q. Holdsworth, C. H. Asma, E. Tai, Y. C. Chatziioannou, A. Leahy, R. M. Model-based normalization for iterative 3D PET image reconstruction.
Physics in Medicine and Biology.
2002;
47(15):
2773-2784.
Kudo, T. Fukuchi, K. Annala, A. J. Chatziioannou, A. F. Allada, V. Dahlbom, M. Tai, Y. C. Inubushi, M. Huang, S. C. Cherry, S. R. Phelps, M. E. Schelbert, H. R. Noninvasive measurement of myocardial activity concentrations and perfusion defect sizes in rats with a new small-animal positron emission tomograph.
Circulation.
2002;
106(1):
118-123.
Kudo, T. Fukuchi, K. Annala, A. J. Chatziioannou, A. F. Allada, V. Dahlbom, M. Tai, Y. C. Inubushi, M. Huang, S. C. Cherry, S. R. Phelps, M. E. Schelbert, H. R. Noninvasive measurement of myocardial activity concentrations and perfusion defect sizes in rats with a new small-animal positron emission tomograph.
Circulation.
2002;
106(1):
118-123.
Weber, S. Bruyndonckx, P. Chatziioannou, A. F. Clark, J. C. Daube-Witherspoon, M. E. Di Domenico, G. Zavattini, G. Honer, M. Huber, J. Karp, J. S. Laforest, R. Muehllehner, G. Pichler, B. J. Seidel, J. Siegel, S. Spinks, T. Tai, Y. C. Vaquero, J. J. Performance measurements of small animal positron emission tomographs..
Journal of Nuclear Medicine.
2002;
43(5):
59p-59p.
Huang, S. C. McBride, W. Stout, D. Sitko, J. Liao, Y. P. Daigle, J. Chatziioannou, A. Satyamurthy, N. Barrio, J. R. Phelps, M. E. Post-irradiation temporal changes in glucose metabolism and cell proliferation in implanted murine tumors as measured by FDG and FLT PET..
Journal of Nuclear Medicine.
2002;
43(5):
25p-25p.
Huang, S. C. McBride, W. Stout, D. Sitko, J. Liao, Y. P. Daigle, J. Chatziioannou, A. Satyamurthy, N. Barrio, J. R. Phelps, M. E. Post-irradiation temporal changes in glucose metabolism and cell proliferation in implanted murine tumors as measured by FDG and FLT PET..
Journal of Nuclear Medicine.
2002;
43(5):
25p-25p.
Berger, F. Lee, Y. P. Loening, A. M. Chatziioannou, A. Freedland, S. J. Leahy, R. Lieberman, J. R. Belldegrun, A. S. Sawyers, C. L. Gambhir, S. S. Whole-body skeletal imaging in mice utilizing microPET: optimization of reproducibility and applications in animal models of bone disease.
European Journal of Nuclear Medicine and Molecular Imaging.
2002;
29(9):
1225-1236.
Y. Shao, S.R. Cherry, A. Chatziioannou Design and development of 1mm resolution PET detectors with position sensitive PMT?s..
Nucl. Instr. Meth. Phys. Res. A
2002;
477:
486-490.
D. Shattuck, J. Rapela, E. Asma, A. Chatziioannou, J. Qi, and R.M. Leahy Internet-Based 3D PET Image Reconstruction Using a Beowulf PC Cluster..
Physics in Medicine and Biology
2002;
47:
2785-2795.
T. Kudo, K. Fukuchi, A. Annala, A. Chatziioannou, V. Allada, M. Dahlbom, Y.C. Tai, M. Inubushi, S. C. Huang, S. R. Cherry, M. E. Phelps, H. Schelbert Non-invasive Measurement of Myocardial Activity Concentrations and Perfusion Defect Sizes in Rats with a new Small Animal Positron Emission Tomograph..
Circulation
2002;
106:
118-123.
Holdsworth, C. Chatziioannou, A. Li, Q. Leahy, R. Levin, C. Janecek, M. Dahlbom, M. Hoffman, E. Data correction techniques for improving the quantitative accuracy of microPET..
Journal of Nuclear Medicine.
2001;
42(5):
201p-201p.
Chatziioannou, A. Tai, Y. C. Doshi, N. Cherry, S. R. Detector development for microPET II: a 1 mu l resolution PET scanner for small animal imaging.
Physics in Medicine and Biology.
2001;
46(11):
2899-2910.
Holdsworth, C. Bai, B. Leahy, R. Chatziioannou, A. Dahlbom, M. Levin, C. McElroy, D. Janecek, M. Hoffman, E. Optimization and comparison of clinical 3D PET and 2D PET: Reconstruction and data correction techniques..
Journal of Nuclear Medicine.
2001;
42(5):
199p-199p.
Berger, F. Loening, A. Chatziioannou, A. Zisman, A. Tso, C. Yoneda, T. Lieberman, J. Sawyers, C. Gambhir, S. Optimization of [18F]Fluoride ion whole body skeletal imaging in mice utilizing microPET and microCAT.
European Journal of Nuclear Medicine.
2001;
28(8):
1192-1192.
Tai, Y. C. Chatziioannou, A. Siegel, S. Young, J. Newport, D. Goble, R. N. Nutt, R. E. Cherry, S. R. Performance evaluation of the microPET P4: a PET system dedicated to animal imaging.
Physics in Medicine and Biology.
2001;
46(7):
1845-1862.
A. Chatziioannou, Y.C. Tai, N. Doshi, S.R. Cherry Detector Development for microPET II: A 1 ?L Resolution PET Scanner for Small Animal Imaging..
Physics in Medicine and Biology
2001;
46:
2899-2910.
Slates, R. Chatziioannou, A. Fehlberg, B. Lee, T. Cherry, S. Chemical polishing of LSO crystals to increase light output.
Ieee Transactions on Nuclear Science.
2000;
47(3):
1018-1023.
Chatziioannou, A. Qi, J. Moore, A. Annala, A. Nguyen, K. Leahy, R. Cherry, S. R. Comparison of 3-D maximum a posteriori and filtered backprojection algorithms for high-resolution animal imaging with microPET.
Ieee Transactions on Medical Imaging.
2000;
19(5):
507-512.
Moore, A. H. Osteen, C. L. Chatziioannou, A. F. Hovda, D. A. Cherry, S. R. Quantitative assessment of longitudinal metabolic changes in vivo after traumatic brain injury in the adult rat using FDG-MicroPET.
Journal of Cerebral Blood Flow and Metabolism.
2000;
20(10):
1492-1501.
Chatziioannou, A. Silverman, R. W. Meadors, K. Farquhar, T. H. Cherry, S. R. Techniques to improve the spatial sampling of microPET - A high resolution animal PET tomograph.
Ieee Transactions on Nuclear Science.
2000;
47(2):
422-427.
Slates R, Chatziioannou A, Fehlberg B, Lee T, Cherry SR Chemical Polishing of LSO Crystals to Increase Light Output..
IEEE Trans. Nucl. Sci
2000;
47:
1018-1023.
Chatziioannou A, Qi J, Moore A, Annala A, Nguyen K, Leahy R, Cherry SR Comparison of 3D Maximum A Posteriori and Filtered Backprojection Algorithms for High Resolution Animal Imaging with microPET..
IEEE Trans. Med. Imag
2000;
19:
507-512.
Chatziioannou A, Silverman R, Meadors K, Farquhar T, Cherry SR Techniques to Improve Spatial Sampling of microPET ? a High Resolution Animal PET Tomograph..
IEEE Trans. Nucl. Sci
2000;
47:
422-427.
Farquhar, T. H. Llacer, J. Sayre, J. Tai, Y. C. Chatziioannou, A. Czernin, J. Dahlbom, M. Gambhir, S. Hoh, C. K. Huang, S. C. Levin, C. MacDonald, L. R. Hoffman, E. J. Effects of size, contrast, and signal-to-noise ratio on tumor detection in positron emission tomography..
Journal of Investigative Medicine.
1999;
47(2):
82a-82a.
Cherry, S. R. Shao, Y. Slates, R. B. Wilcut, E. Chatziioannou, A. F. Dahlbom, M. Micropet II - Design of a 1 mm resolution pet scanner for small animal imaging..
Journal of Nuclear Medicine.
1999;
40(5):
75p-75p.
Chatziioannou, A. F. Cherry, S. R. Shao, Y. P. Silverman, R. W. Meadors, K. Farquhar, T. H. Pedarsani, M. Phelps, M. E. Performance evaluation of microPET: A high-resolution lutetium oxyorthosilicate PET scanner for animal imaging.
Journal of Nuclear Medicine.
1999;
40(7):
1164-1175.
Chatziioannou A, Cherry SR, Shao Y, Silverman RW, Meadors K, Farquhar TH, Pedarsani M, Phelps ME Performance Evaluation of microPET: A High Resolution LSO PET Scanner for Animal Imaging..
J. Nucl. Med
1999;
40:
1164-1175.
Farquhar, T. H. Chatziioannou, A. Cherry, S. R. An evaluation of exact and approximate 3-D reconstruction algorithms for a high-resolution, small-animal PET scanner.
Ieee Transactions on Medical Imaging.
1998;
17(6):
1073-1080.
Cherry, S. R. Chatziioannou, A. Doshi, N. K. Shao, Y. Silverman, R. W. Annala, A. J. Pedarsani, M. Phelps, M. E. An interactive guide to microPET..
Journal of Nuclear Medicine.
1998;
39(5):
278p-279p.
Farquhar, T. H. Chatziioannou, A. Chinn, G. Dahlbom, M. Hoffman, E. J. An investigation of filter choice for filtered back-projection reconstruction in PET.
Ieee Transactions on Nuclear Science.
1998;
45(3):
1133-1137.
Farquhar, T. H. Llacer, J. Sayre, J. Tai, Y. C. Chatziioannou, A. Cherry, S. R. Czernin, J. Dahlbom, M. Gambhir, S. S. Hoh, C. K. Huang, S. C. Levin, C. S. MacDonald, L. R. Schelbert, H. R. Seltzer, M. A. Silverman, D. H. S. Hoffman, E. J. Effect of lesion contrast, size, and SNR on detectability in PET as measured by ROC analysis.
Journal of Nuclear Medicine.
1998;
39(5):
9p-9p.
Morguet, A. J. Chatziioannou, A. F. Cherry, S. R. Phelps, M. E. Schelbert, H. R. Evaluation of a newly developed small-animal PET scanner in experimental myocardial infarction..
Journal of Nuclear Medicine.
1998;
39(5):
9p-9p.
Qi, J. Y. Leahy, R. M. Cherry, S. R. Chatziioannou, A. Farquhar, T. H. High-resolution 3D Bayesian image reconstruction using the microPET small-animal scanner.
Physics in Medicine and Biology.
1998;
43(4):
1001-1013.
Tai, Y. C. Chatziioannou, A. Dahlbom, M. Hoffman, E. J. Investigation of deadtime characteristics for simultaneous emission-transmission data acquisition in PET.
Ieee Transactions on Nuclear Science.
1998;
45(4):
2200-2204.
Morguet, A. J. Chatziioannou, A. F. Cherry, S. R. Phelps, M. E. Schelbert, H. R. Quantitation of infarct size in rat myocardium using F-18 deoxyglucose and a new high-resolution microPET system.
Journal of the American College of Cardiology.
1998;
31(2):
480a-480a.
Chatziioannou, A. Cherry, S. R. Silverman, R. W. Meadors, K. Farquhar, T. Phelps, M. E. Techniques to improve spatial sampling of a high resolution animal tomograph.
Journal of Nuclear Medicine.
1998;
39(5):
133p-133p.
T. H. Farquhar, A. Chatziioannou, G. Chinn, M. Dahlbom, and E. J. Hoffman An investigation of filter choice for filtered back-projection reconstruction in PET..
IEEE Trans. Nucl. Sci.
1998;
45:
1133-1137.
S. R. Cherry, A. Chatziioannou, Y. Shao, R. W. Silverman, K. Meadors, and M. E. Phelps Brain Imaging in Small Animals Using MicroPET..
Quantitative Functional Brain Imaging with Positron Emission Tomography
1998;
3-9.
Y. C. Tai, A. Chatziioannou, M. Dahlbom, E. J. Hoffman Investigation of Deadtime Characteristics for Simultaneous Emission-Transmission Data Acquisition in PET..
IEEE Trans. Nucl. Sci.
1998;
45:
2200-2204.
Chan, M. T. Leahy, R. M. Mumcuoglu, E. U. Cherry, S. R. Czernin, J. Chatziioannou, A. Comparing lesion detection performance for PET image reconstruction algorithms: A case study.
Ieee Transactions on Nuclear Science.
1997;
44(4):
1558-1563.
Leahy, R. M. Chan, M. T. Cherry, S. R. Mumcuoglu, E. U. Czernin, J. Chatziioannou, A. Comparison of lesion detection performance for PET image reconstruction using channelized hotelling observers.
Journal of Nuclear Medicine.
1997;
38(5):
286-286.
Tai, Y. C. Chatziioannou, A. Dahlbom, M. Hoffman, E. J. Evaluation of a deadtime correction technique for simultaneous emission-transmission data acquisition in PET..
Journal of Nuclear Medicine.
1997;
38(5):
424-424.
Chatziioannou, A. Cherry, S. R. Shao, Y. Silverman, R. W. Meadors, K. Farquhar, T. Phelps, M. E. MicroPET I: Performance evaluation of a very high resolution PET scanner for imaging small animals..
Journal of Nuclear Medicine.
1997;
38(5):
19-19.
Cherry, S. R. Shao, Y. Silverman, R. W. Meadors, K. Siegel, S. Chatziioannou, A. Young, J. W. Jones, W. F. Moyers, J. C. Newport, D. Boutefnouchet, A. Farquhar, T. H. Andreaco, M. Paulus, M. J. Binkley, D. M. Nutt, R. Phelps, M. E. MicroPET: A high resolution PET scanner for imaging small animals.
Ieee Transactions on Nuclear Science.
1997;
44(3):
1161-1166.
Martinez, Z. A. Colgan, M. Baxter, L. R. Quintana, J. Siegel, S. Chatziioannou, A. Cherry, S. R. Mazziotta, J. C. Phelps, M. E. Oral F-18-fluoro-2-deoxyglucose for primate PET studies without behavioral restraint: Demonstration of principle.
American Journal of Primatology.
1997;
42(3):
215-224.
M. Chan, R. Leahy, E. Mumcuoglu, S. R. Cherry, J. Czernin, A. Chatziioannou Comparing Lesion Detection Performance for PET Image Reconstruction: a Case Study..
IEEE Trans. Nucl. Sci.
1997;
44:
1558-1563.
S. R. Cherry, Y. Shao, R. W. Silverman, K. Meadors, S. Siegel, A. Chatziioannou, J. W. Young, W. F. Jones, J. C. Moyers, D. Newport, A. Boutefnouchet, T. H. Farquhar, M. Andreaco, M. J. Paulus, D. M. Binkley, R. Nutt, M. E. Phelps MicroPET: A High Resolution PET Scanner for Imaging Small Animals..
IEEE Trans. Nucl. Sci.
1997;
44:
1161-1166.
Z. A. Martinez, M. Colgan, L. R. Baxter, J. Quintana, S. Siegel, A. Chatziioannou, S. R. Cherry, J. C. Mazziotta, M. E. Phelps Oral F-18 Fluoro-2-Deoxyglucose For Primate Pet Studies Without Behavioral Restraint - Demonstration Of Principle..
American Journal Of Primatology
1997;
42:
215-224.
Chatziioannou, A. Dahlbom, M. Detailed investigation of transmission and emission data smoothing protocols and their effects on emission images.
Ieee Transactions on Nuclear Science.
1996;
43(1):
290-294.
Chatziioannou, A. Dahlbom, M. Hoh, C. K. Whole body pet attenuation correction with transmission image segmentation..
Journal of Nuclear Medicine.
1996;
37(5):
20-20.
A. Chatziioannou and M. Dahlbom Detailed Investigation of Transmission and Emission Data Smoothing Protocols and their Effects on Emission Images..
IEEE Trans. Nucl. Sci.
1996;
43:
290-294.
Chatziioannou, A. Dahlbom, M. Hoh, C. J. Study on the Use of Transmission Scans for Whole-Body Pet Attenuation Correction.
Ieee Transactions on Nuclear Science.
1994;
41(4):
1545-1550.
A. Chatziioannou, M. Dahlbom and C. K. Hoh Study on the use of Transmission Scans for Whole Body PET Attenuation Correction..
1994;
41:
1545-1550.
Kimme-Smith, C. Chatziioannou, A. Mammography Focal Spot Measurement with a Star Pattern - Techniques to Avoid Inaccuracies.
Medical Physics.
1993;
20(1):
93-97.
C-K Smith and A Chatziioannou Mammography focal spot measurement with a star pattern: Techniques to avoid inaccuracies..
Medical Physics
1993;
20:
93-97.
Dahlbom, M. Yu, D. C. Cherry, S. R. Chatziioannou, A. Hoffman, E. J. Methods for Improving Image Quality in Whole-Body Pet Scanning.
Ieee Transactions on Nuclear Science.
1992;
39(4):
1079-1083.
M. Dahlbom, D. C. Yu, S. R. Cherry, A. Chatziioannou and E. J. Hoffman Methods for Improving Image Quality in Whole body PET Scanning..
IEEE Trans. Nucl. Sci.
1992;
39:
1079-1083.
Marx, J Imaging. Animal models: live and in color..
Science. .
2003;
302(5652):
1880-2.
Bai, B Li, Q Holdsworth, CH Asma, E Tai, YC Chatziioannou, A Leahy, RM Model-based normalization for iterative 3D PET image reconstruction..
Physics in medicine and biology. .
2002;
47(15):
2773-84.
Tai, C Chatziioannou, A Siegel, S Young, J Newport, D Goble, RN Nutt, RE Cherry, SR Performance evaluation of the microPET P4: a PET system dedicated to animal imaging..
Physics in medicine and biology. .
2001;
46(7):
1845-62.
Farquhar, TH Chatziioannou, A Cherry, SR An evaluation of exact and approximate 3-D reconstruction algorithms for a high-resolution, small-animal PET scanner..
IEEE transactions on medical imaging. .
1998;
17(6):
1073-80.
Qi, J Leahy, RM Cherry, SR Chatziioannou, A Farquhar, TH High-resolution 3D Bayesian image reconstruction using the microPET small-animal scanner..
Physics in medicine and biology. .
1998;
43(4):
1001-13.
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